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Article

The quantitative impact of read mapping to non-native reference genomes in comparative RNA-Seq studies.

PloS one - 1 Jan 2017

Price Adam, Gibas Cynthia

Abstract excerpt

Sequence read alignment to a reference genome is a fundamental step in many genomics studies. Accuracy in this fundamental step is crucial for correct interpretation of biological data. In cases where two or more closely related bacterial strains are being studied, a common approach is to simply map reads from all strains to a common reference genome, whether because there is no closed reference for some strains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28700635
DOI: 10.1371/journal.pone.0180904
PMCID: PMC5507458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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