Article

Towards accurate, reference-free differential expression: A comprehensive evaluation of long-read <i>de novo</i> transcriptome assembly

2025-02-07

Abstract excerpt

Long-read RNA sequencing has significantly advanced transcriptomics by enabling the full length of transcripts to be assessed. However, current analysis methods often depend on a high-quality reference genome and gene annotation. Recently, de novo assembly methods have been developed to utilise long-read data in cases where a reference genome is unavailable, such as in non-model organisms. Despite the potential o...

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Literature Corpus work: 1d8b5d9b-2583-569f-9b64-5188d8c517a6
DOI: 10.1101/2025.02.02.635999

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