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Article

Endogenous sequence patterns predispose the repair modes of CRISPR/Cas9-induced DNA double-stranded breaks in Arabidopsis thaliana.

The Plant journal : for cell and molecular biology - 1 Oct 2017

Vu Giang T H, Cao Hieu X, Fauser Friedrich, Reiss Bernd, Puchta Holger, Schubert Ingo

Abstract excerpt

The possibility to predict the outcome of targeted DNA double-stranded break (DSB) repair would be desirable for genome editing. Furthermore the consequences of mis-repair of potentially cell-lethal DSBs and the underlying pathways are not yet fully understood. Here we study the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-induced mutation spectra at three selected endogenous loci in...

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Source

Identifiers

PMID: 28696528
DOI: 10.1111/tpj.13634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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