Article
Deletion-bias in DNA double-strand break repair differentially contributes to plant genome shrinkage.
The New phytologist - 1 Jun 2017
Vu Giang T H, Cao Hieu X, Reiss Bernd, Schubert Ingo
Abstract excerpt
In order to prevent genome instability, cells need to be protected by a number of repair mechanisms, including DNA double-strand break (DSB) repair. The extent to which DSB repair, biased towards deletions or insertions, contributes to evolutionary diversification of genome size is still under debate. We analyzed mutation spectra in Arabidopsis thaliana and in barley (Hordeum vulgare) by PacBio sequencing of...
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