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Article

Repair of adjacent single-strand breaks is often accompanied by the formation of tandem sequence duplications in plant genomes.

Proceedings of the National Academy of Sciences of the United States of America - 28 Jun 2016

Schiml Simon, Fauser Friedrich, Puchta Holger

Abstract excerpt

Duplication of existing sequences is a major mechanism of genome evolution. It has been previously shown that duplications can occur by replication slippage, unequal sister chromatid exchange, homologous recombination, and aberrant double-strand break-induced synthesis-dependent strand annealing reactions. In a recent study, the abundant presence of short direct repeats was documented by comparative...

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PMID: 27307441
DOI: 10.1073/pnas.1603823113
PMCID: PMC4932966

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