Article
Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young.
Pediatric diabetes - 1 Mar 2018
Frohnert Brigitte I, Laimighofer Michael, Krumsiek Jan, Theis Fabian J, Winkler Christiane, Norris Jill M, Ziegler Anette-Gabriele, Rewers Marian J, Steck Andrea K
Abstract excerpt
BACKGROUND: Genetic predisposition for type 1 diabetes (T1D) is largely determined by human leukocyte antigen (HLA) genes; however, over 50 other genetic regions confer susceptibility. We evaluated a previously reported 10-factor weighted model derived from the Type 1 Diabetes Genetics Consortium to predict the development of diabetes in the Diabetes Autoimmunity Study in the Young (DAISY) prospective cohort....
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