Article
Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes.
Diabetologia - 1 Dec 2014
Winkler Christiane, Krumsiek Jan, Buettner Florian, Angermüller Christof, Giannopoulou Eleni Z, Theis Fabian J, Ziegler Anette-Gabriele, Bonifacio Ezio
Abstract excerpt
AIMS/HYPOTHESIS: More than 40 regions of the human genome confer susceptibility for type 1 diabetes and could be used to establish population screening strategies. The aim of our study was to identify weighted sets of SNP combinations for type 1 diabetes prediction. METHODS: We applied multivariable logistic regression and Bayesian feature selection to the Type 1 Diabetes Genetics Consortium (T1DGC) dataset with...
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