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Article

Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers.

Pediatric diabetes - 1 Aug 2014

Steck Andrea K, Dong Fran, Wong Randall, Fouts Alexandra, Liu Edwin, Romanos Jihane, Wijmenga Cisca, Norris Jill M, Rewers Marian J

Abstract excerpt

OBJECTIVE: The purpose of this study was to explore whether non-human leukocyte antigen (non-HLA) genetic markers can improve type 1 diabetes(T1D) prediction in a prospective cohort with high-risk HLA-DR,DQ genotypes. METHODS: The Diabetes Autoimmunity Study in the Young (DAISY) follows prospectively for the development of T1D and islet autoimmunity (IA)children at increased genetic risk. A total of 1709...

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Share to Adaptor Proteins, Signal Transducing
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to HLA Antigens

Share to HLA-DQ Antigens

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Open in PubMed Open full text

Identifiers

PMID: 25075402
DOI: 10.1111/pedi.12092
PMCID: PMC4116638

Genes

PTPN22
GLIS3
IFIH1
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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