Article
Autoantibodies in the Extraintestinal Manifestations of Celiac Disease.
Nutrients - 20 Aug 2018
Yu Xuechen B, Uhde Melanie, Green Peter H, Alaedini Armin
Abstract excerpt
Increased antibody reactivity towards self-antigens is often indicative of a disruption of homeostatic immune pathways in the body. In celiac disease, an autoimmune enteropathy triggered by the ingestion of gluten from wheat and related cereals in genetically predisposed individuals, autoantibody reactivity to transglutaminase 2 is reflective of the pathogenic role of the enzyme in driving the associated...
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