Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice

10 Jul 2017

Abstract excerpt

Zika virus (ZIKV) infection during pregnancy leads to devastating fetal outcomes, including intrauterine growth restriction and microcephaly. Greater understanding of mechanisms underlying ZIKV maternal-fetal transmission is needed to develop new therapeutic interventions. Here, we define an important role for the autophagy pathway in ZIKV vertical transmission. ZIKV infection induced autophagic activity in human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 28694387
DOI: 10.1084/jem.20170957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant micePMID 28694387Read ↗

Zika virus infection during pregnancy and induced brain pathology in beclin1-deficient mouse modelSemantic proximity Read ↗

Autophagy in Zika Virus Infection: A Possible Therapeutic Target to Counteract Viral ReplicationSemantic proximity Read ↗

Downregulation of Transcriptional Activity, Increased Inflammation, and Damage in the Placenta Following in utero Zika Virus Infection Is Associated With Adverse Pregnancy OutcomesSemantic proximity Read ↗

ATG16L1 governs placental infection risk and preterm birth in mice and womenSemantic proximity Read ↗

Maternal-Fetal Transmission of Zika Virus: Routes and Signals for InfectionSemantic proximity Read ↗

Zika Virus Infects Early- and Midgestation Human Maternal Decidual Tissues, Inducing Distinct Innate Tissue Responses in the Maternal-Fetal InterfaceSemantic proximity Read ↗

EVs Containing Host Restriction Factor IFITM3 Inhibited ZIKV Infection of Fetuses in Pregnant Mice through Trans-placenta DeliverySemantic proximity Read ↗

Fetal MAVS and type I IFN signaling pathways control ZIKV infection in the placenta and maternal deciduaSemantic proximity Read ↗

mTOR signaling regulates Zika virus replication bidirectionally through autophagy and protein translationSemantic proximity Read ↗

The HAVCR1-centric host factor network drives Zika virus vertical transmissionSemantic proximity Read ↗

Possible Routes for Zika Virus Vertical Transmission in Human Placenta: A Comprehensive ReviewSemantic proximity Read ↗

Role of autophagy in Zika virus infection and pathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.