Article

Zika virus infection during pregnancy and induced brain pathology in beclin1-deficient mouse model

2019-11-15

Abstract excerpt

<h4>ABSTRACT</h4> We investigated the role of the autophagy protein, Beclin1, in the replication and disease of Zika virus (ZIKV) in pregnant dams and their offspring using Beclin1-deficient (Atg6 +/− ) and wild-type (Atg6 +/+ ) mouse model infected with the Honduran (R103451), Puerto Rican (PRVABC59), and the Uganda (MR766) strains of ZIKV. Pregnant dams infected subcutaneously at embryonic stage (E)9 showed v...

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Literature Corpus work: ac7e4e69-38fc-5014-b619-f2c2d011219d
DOI: 10.1101/843813

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