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Autophagy in Zika Virus Infection: A Possible Therapeutic Target to Counteract Viral Replication

28 Feb 2019

Abstract excerpt

Zika virus (ZIKV) still constitutes a public health concern, however, no vaccines or therapies are currently approved for treatment. A fundamental process involved in ZIKV infection is autophagy, a cellular catabolic pathway delivering cytoplasmic cargo to the lysosome for degradation-considered as a primordial form of innate immunity against invading microorganisms. ZIKV is thought to inhibit the Akt-mTOR...

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PMID: 30823365
DOI: 10.3390/ijms20051048

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