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Article

mTOR signaling regulates Zika virus replication bidirectionally through autophagy and protein translation

22 Dec 2022

Abstract excerpt

Zika virus (ZIKV) reemerged in 2016 and attracted much more attention worldwide. To date, the limited knowledge of ZIKV interactions with host cells in the early stages of infection impedes the prevention of viral epidemics and the treatment of ZIKV disease. The mammalian target of rapamycin (mTOR) signaling pathway plays an essential role in the regulation of autophagy and protein synthesis during multiple viral...

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PMID: 36546404
DOI: 10.1002/jmv.28422

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