Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis

10 Jul 2017

Abstract excerpt

Erf is a gene for a ubiquitously expressed Ets DNA-binding domain-containing transcriptional repressor. Erf haploinsufficiency causes craniosynostosis in humans and mice, while its absence in mice leads to failed chorioallantoic fusion and death at embryonic day 10.5 (E10.5). In this study, we show that Erf is required in all three waves of embryonic hematopoiesis. Mice lacking Erf in the embryo proper exhibited...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Pregnancy and preeclampsia studies
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28694332
DOI: 10.1128/mcb.00183-17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive HematopoiesisPMID 28694332Read ↗

Transcriptional repressor erf determines extraembryonic ectoderm differentiation.Semantic proximity Read ↗

A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryoSemantic proximity Read ↗

Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.Semantic proximity Read ↗

Erythroid overproduction of erythroferrone causes iron overload and developmental abnormalities in miceSemantic proximity Read ↗

Regulation of Human Erythroferrone ExpressionSemantic proximity Read ↗

Overexpression of Ets-1 in human hematopoietic progenitor cells blocks erythroid and promotes megakaryocytic differentiationSemantic proximity Read ↗

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo.Semantic proximity Read ↗

The core-binding factor beta subunit is required for bone formation and hematopoietic maturation.Semantic proximity Read ↗

Functional conservation of erythropoietin signaling in zebrafishSemantic proximity Read ↗

Growth Factor Independence 1b (Gfi1b) Is Important for the Maturation of Erythroid Cells and the Regulation of Embryonic Globin ExpressionSemantic proximity Read ↗

Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus.Semantic proximity Read ↗

A critical role for endoglin in the emergence of blood during embryonic developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.