Article
Is MMP-7 gene polymorphism a possible risk factor for chronic obstructive pulmonary disease in Turkish patients.
Genetic testing and molecular biomarkers - 1 Jun 2012
Mogulkoc Umit, Coskunpinar Ender, Aynaci Engin, Cağlar Emel, Ortakoylu Mediha Gonenc, Ozkan Gokhan, Oltulu Yasemin Musteri, Eraltan Ilhan Yaylim
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that leads to fixed narrowing of small airways and alveolar wall destruction (emphysema). This study was performed to test the association between MMP-7 (rs155668818) and MMP-12 (rs56184183) polymorphisms in the MMP-7 gene and COPD risk and its severity in the Turkish population. MMP-7 and MMP-12 polymorphisms were genotyped in 85...
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