Article
Endothelial nitric oxide synthase gene polymorphisms and essential hypertension in Han Chinese.
Genetics and molecular research : GMR - 21 Sept 2010
Wang H G, Wang J L, Chang P, Cao F L, Liu X C, Ma Y B, Zhai G X, Gao H Q
Abstract excerpt
We examined the effect of polymorphisms in the endothelial nitric oxide synthase gene on the risk for essential hypertension in a Han Chinese population through a meta-analysis of data from 15 studies. Associations between increased risk for essential hypertension and 4b/a were obtained in a dominant model and allele contrast (aa + ab vs bb: odds ratio (OR)(FE) = 1.26, 95% confidence interval (CI) = 1.10-1.44; a...
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