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Article

Association of endothelin-1 gene variant with hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Jan 2003

Jin Jing Ji, Nakura Jun, Wu Zhihong, Yamamoto Miyuki, Abe Michiko, Tabara Yasuharu, Yamamoto Yoshikuni, Igase Michiya, Kohara Katsuhiko, Miki Tetsuro

Abstract excerpt

Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide produced by endothelial and smooth muscle cells. Many lines of biological evidence suggest that the ET-1 gene is a candidate gene for hypertension. Moreover, recent association studies suggested that a G/T polymorphism with an amino acid s...

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Identifiers

PMID: 12511547
DOI: 10.1161/01.hyp.0000043680.75107.cf

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12511547-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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