Article
Genotyping assay for differentiation of wild-type and vaccine viruses in subjects immunized with live attenuated influenza vaccine.
PloS one - 1 Jan 2017
Matyushenko Victoria, Isakova-Sivak Irina, Smolonogina Tatiana, Dubrovina Irina, Tretiak Tatiana, Rudenko Larisa
Abstract excerpt
Live attenuated influenza vaccines (LAIVs) are considered as safe and effective tool to control influenza in different age groups, especially in young children. An important part of the LAIV safety evaluation is the detection of vaccine virus replication in the nasopharynx of the vaccinees, with special attention to a potential virus transmission to the unvaccinated close contacts. Conducting LAIV clinical trials...
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