Article
TERT C228T mutation in non-malignant bladder urothelium is associated with intravesical recurrence for patients with non-muscle invasive bladder cancer.
Molecular oncology - 1 Oct 2020
Hayashi Yujiro, Fujita Kazutoshi, Nojima Satoshi, Tomiyama Eisuke, Matsushita Makoto, Koh Yoko, Nakano Kosuke, Wang Cong, Ishizuya Yu, Kato Taigo, Hatano Koji, Kawashima Atsunari, Ujike Takeshi, Uemura Motohide, Imamura Ryoichi, Morii Eiichi, Nonomura Norio
Abstract excerpt
Telomerase reverse transcriptase (TERT) promoter mutations are frequently found in tumors or urine from patients with urothelial carcinoma (UC). TERT promoter mutations are also detected in urine from patients with no evidence of cancer but are associated with subsequent UC development. Mutations in the TERT promoter are thought to be present in nonmalignant urothelium (NMU) during early stages of tumor formation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.