Article
SPINK5 is associated with early-onset and CHI3L1 with late-onset atopic dermatitis.
International journal of immunogenetics - 1 Oct 2017
Dežman K, Korošec P, Rupnik H, Rijavec M
Abstract excerpt
We have recently showed that filaggrin (FLG) mutations are associated only with early-onset of AD, but not with late-onset of AD. Consequently, other susceptibility genes should receive attention, especially in patients with late-onset of AD. Our aim was to assess the associations between development of AD and the polymorphisms rs2303067 in SPINK5 and rs490928 in CHI3L1. A study population of 241 AD patients and...
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