Article
Filaggrin loss-of-function mutations are not associated with atopic dermatitis that develops in late childhood or adulthood.
The British journal of dermatology - 1 Feb 2015
Rupnik H, Rijavec M, Korošec P
Abstract excerpt
BACKGROUND: The influence of filaggrin gene (FLG) mutations on early- vs. late-onset development of atopic dermatitis (AD), allergic contact dermatitis (ACD) and chronic irritant contact dermatitis (CICD) is not completely understood. OBJECTIVES: To assess the association between FLG mutations and development of AD, ACD and CICD. METHODS: This study assessed 241 patients with AD. AD developed during infancy in 85...
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