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Article

Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis.

The Journal of allergy and clinical immunology - 1 Mar 2022

Sliz Eeva, Huilaja Laura, Pasanen Anu, Laisk Triin, Reimann Ene, Mägi Reedik, Hannula-Jouppi Katariina, Peltonen Sirkku, Salmi Teea, Koulu Leena, Tasanen Kaisa, Kettunen Johannes

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) is a common chronic inflammatory skin disease with high heritability. Previous genome-wide association studies have identified several loci predisposing to AD. These findings explain approximately 30% of the variance in AD susceptibility, suggesting that further work is required to fully understand the genetic underpinnings. OBJECTIVE: We sought to gain additional understanding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34454985
DOI: 10.1016/j.jaci.2021.07.043

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