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Article

Ongoing Electroencephalographic Activity Associated with Cortical Arousal in Transgenic PDAPP Mice (hAPP V717F).

Current Alzheimer research - 1 Jan 2018

Del Percio Claudio, Drinkenburg Wilhelmus, Lopez Susanna, Limatola Cristina, Bastlund Jesper F, Christensen Ditte Z, Pedersen Jan T, Forloni Gianluigi, Frasca Angelisa, Noe Francesco M, Bentivoglio Marina, Fabene Paolo F, Bertini Giuseppe, Colavito Valeria, Dix Sophie, Ferri Raffaele, Bordet Regis, Richardson Jill C, Babiloni Claudio

Abstract excerpt

BACKGROUND: It has been shown that theta (6-10 Hz) and delta (1-6 Hz) ongoing electroencephalographic (EEG) rhythms revealed variations in the cortical arousal in C57 Wild Type (WT) mice during cage exploration (active condition) compared to awake quiet behavior (passive condition; IMI PharmaCog project, www.pharmacog.eu). OBJECTIVE: The objective was to test if these EEG rhythms might be abnormal in old PDAPP...

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PMID: 28675996
DOI: 10.2174/1567205014666170704113405

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