Neuropsychological effects of the CSMD1 genome-wide associated schizophrenia risk variant rs10503253.

doi:10.1111/gbb.12016

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Article

Neuropsychological effects of the CSMD1 genome-wide associated schizophrenia risk variant rs10503253.

Genes, brain, and behavior - 1 Mar 2013

Donohoe G, Walters J, Hargreaves A, Rose E J, Morris D W, Fahey C, Bellini S, Cummins E, Giegling I, Hartmann A M, Möller H-J, Muglia P, Owen M J, Gill M, O'Donovan M C, Tropea D, Rujescu D, Corvin A

Abstract excerpt

The single-nucleotide polymorphism (SNP) rs10503253, located within the CUB and Sushi multiple domains-1 (CSMD1) gene on 8p23.2, was recently identified as genome-wide significant for schizophrenia (SZ), but is of unknown function. We investigated the neurocognitive effects of this CSMD1 variant in vivo in patients and healthy participants using behavioral and imaging measures of brain structure and function. We...

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PMID: 23320435
DOI: 10.1111/gbb.12016

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CSMD1

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