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Article

Antigen-specific effector CD8 T cells regulate allergic responses via IFN-γ and dendritic cell function.

The Journal of allergy and clinical immunology - 1 Jun 2012

Tang Yafang, Guan Shou Ping, Chua Benson Y L, Zhou Qian, Ho Adrian W S, Wong Kenneth H S, Wong Kok Loon, Wong W S Fred, Kemeny David M

Abstract excerpt

BACKGROUND: Previous studies have shown that CD8 T cells can both prevent and cause allergic responses. However, the underlying mechanisms remain to be elucidated. OBJECTIVE: We aim to investigate the potential of CD8 T cells with different IFN-γ expressions to modulate the elicitation of allergic inflammation following ovalbumin (OVA) challenge and investigate the underlying mechanisms. METHODS: To study the...

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Identifiers

PMID: 22385629
DOI: 10.1016/j.jaci.2011.12.976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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