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Article

Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3.

The Biochemical journal - 1 Mar 2006

Zhang Jing, Tackaberry Tracey, Ritzel Mabel W L, Raborn Taylor, Barron Gerry, Baldwin Stephen A, Young James D, Cass Carol E

Abstract excerpt

hCNT3 (human concentrative nucleoside transporter 3) is a nucleoside-sodium symporter that transports a broad range of naturally occurring purine and pyrimidine nucleosides as well as anticancer nucleoside drugs. To understand its uridine binding and translocation mechanisms, a cysteine-less version of hCNT3 was constructed and used for cysteine-accessibility and permeant-protection assays. Cysteine-less hCNT3,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16271041
DOI: 10.1042/BJ20051476
PMCID: PMC1408669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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