Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subcellular distribution and membrane topology of the mammalian concentrative Na+-nucleoside cotransporter rCNT1.

The Journal of biological chemistry - 27 Jul 2001

Hamilton S R, Yao S Y, Ingram J C, Hadden D A, Ritzel M W, Gallagher M P, Henderson P J, Cass C E, Young J D, Baldwin S A

Abstract excerpt

The rat transporter rCNT1 is the archetype of a family of concentrative nucleoside transporters (CNTs) found both in eukaryotes and in prokaryotes. In the present study we have used antibodies to investigate the subcellular distribution and membrane topology of this protein. rCNT1 was found to be expressed predominantly in the brush-border membranes of the polarized epithelial cells of rat jejunum and renal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asparagine
Share to Glycosylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intestinal Mucosa

Share to Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase

Share to Oocytes

Share to Tissue Distribution

Share to Uridine

Share to Xenopus

Source

Identifiers

PMID: 11375981
DOI: 10.1074/jbc.M100518200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subcellular distribution and membrane topology of the mammalian concentrative Na+-nucleoside cotransporter rCNT1.PMID 11375981Read ↗

Conserved residues F316 and G476 in the concentrative nucleoside transporter 1 (hCNT1) affect guanosine sensitivity and membrane expression, respectively.Semantic proximity Read ↗

Sorting of rat SPNT in renal epithelium is independent of N-glycosylation.Semantic proximity Read ↗

Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2.Semantic proximity Read ↗

Concentrative nucleoside transporter 1 (hCNT1) promotes phenotypic changes relevant to tumor biology in a translocation-independent manner.Semantic proximity Read ↗

Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells.Semantic proximity Read ↗

The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoformsSemantic proximity Read ↗

Cloning and Characterization of Two Human Polyspecific Organic Cation TransportersSemantic proximity Read ↗

Structure and function of cationic amino acid transporters (CATs).Semantic proximity Read ↗

Fine tuning of rabbit equilibrative nucleoside transporter activity by an alternatively spliced variant.Semantic proximity Read ↗

Human Concentrative Nucleoside Transporter 3 (hCNT3, SLC28A3) Forms a Cyclic Homotrimer.Semantic proximity Read ↗

A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.Semantic proximity Read ↗

The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.