Article
Joint genotype- and ancestry-based genome-wide association studies in admixed populations.
Genetic epidemiology - 1 Sept 2017
Szulc Piotr, Bogdan Malgorzata, Frommlet Florian, Tang Hua
Abstract excerpt
In genome-wide association studies (GWAS) genetic loci that influence complex traits are localized by inspecting associations between genotypes of genetic markers and the values of the trait of interest. On the other hand, admixture mapping, which is performed in case of populations consisting of a recent mix of two ancestral groups, relies on the ancestry information at each locus (locus-specific ancestry)....
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