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Article

A molecular portrait of epithelial–mesenchymal plasticity in prostate cancer associated with clinical outcome

7 Sept 2018

Abstract excerpt

The propensity of cancer cells to transition between epithelial and mesenchymal phenotypic states via the epithelial-mesenchymal transition (EMT) program can regulate metastatic processes, cancer progression, and treatment resistance. Transcriptional investigations using reversible models of EMT, revealed the mesenchymal-to-epithelial reverting transition (MErT) to be enriched in clinical samples of metastatic...

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PMID: 30194451
DOI: 10.1038/s41388-018-0488-5

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