Epithelial-mesenchymal transition markers screened in a cell-based model and validated in lung adenocarcinoma

Abstract excerpt

BACKGROUND: Re-capture of the differences between tumor and normal tissues observed at the patient level in cell cultures and animal models is critical for applications of these cancer-related differences. The epithelial-mesenchymal transition (EMT) process is essential for tumor migratory and invasive capabilities. Although plenty of EMT markers are revealed, molecular features during the early stages of EMT are...

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