Article
Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation.
Developmental biology - 1 Sept 2017
Gallagher Thomas L, Tietz Kiel T, Morrow Zachary T, McCammon Jasmine M, Goldrich Michael L, Derr Nicolas L, Amacher Sharon L
Abstract excerpt
Vertebrate segmentation is controlled by the segmentation clock, a molecular oscillator that regulates gene expression and cycles rapidly. The expression of many genes oscillates during segmentation, including hairy/Enhancer of split-related (her or Hes) genes, which encode transcriptional repressors that auto-inhibit their own expression, and deltaC (dlc), which encodes a Notch ligand. We previously identified...
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