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Article

Differential in vivo requirements for oligomerization during Groucho-mediated repression.

EMBO reports - 1 Jan 2008

Jennings Barbara H, Wainwright S Mark, Ish-Horowicz David

Abstract excerpt

The Groucho (Gro)/transducin-like enhancer of split family of transcriptional corepressors are implicated in many signalling pathways that are important in development and disease, including those mediated by Notch, Wnt and Hedgehog. Here, we describe a genetic screen in Drosophila that yielded 50 new gro alleles, including the first protein-null allele, and has two mutations in the conserved Q oligomerization...

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Identifiers

PMID: 18034187
DOI: 10.1038/sj.embor.7401122
PMCID: PMC2246631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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