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Article

Identification of Flavin-Containing Monooxygenase 5 (FMO5) as a Regulator of Glucose Homeostasis and a Potential Sensor of Gut Bacteria.

Drug metabolism and disposition: the biological fate of chemicals - 1 Sept 2017

Scott Flora, Gonzalez Malagon Sandra G, O'Brien Brett A, Fennema Diede, Veeravalli Sunil, Coveney Clarissa R, Phillips Ian R, Shephard Elizabeth A

Abstract excerpt

We have previously identified flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic aging. The aim of the present study was to investigate the role of FMO5 in glucose homeostasis and the impact of diet and gut flora on the phenotype of mice in which the Fmo5 gene has been disrupted (Fmo5-/- mice). In comparison with wild-type (WT) counterparts, Fmo5-/- mice are resistant to age-related changes in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28646079
DOI: 10.1124/dmd.117.076612
PMCID: PMC5539585

Genes

FMO5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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