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Article

Mechanotransduction properties of the cytoplasmic tail of PECAM-1.

Biology of the cell - 1 Aug 2017

Snyder Jessica L, McBeath Elena, Thomas Tamlyn N, Chiu Yi Jen, Clark Robert L, Fujiwara Keigi

Abstract excerpt

BACKGROUND INFORMATION: Vascular endothelial cells (ECs) are a well-known cell system used in the study of mechanobiology. Using cultured ECs, we found that platelet EC adhesion molecule 1 (PECAM-1, CD31), a cell adhesion protein localised to regions of EC-EC contact, was rapidly tyrosine phosphorylated in ECs exposed to shear or cyclic stretch. Src-homology 2 domain-containing protein tyrosine phosphatase 2...

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Identifiers

PMID: 28643869
DOI: 10.1111/boc.201600079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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