Article
Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression.
The Journal of biological chemistry - 2 Aug 1996
Sun J, Williams J, Yan H C, Amin K M, Albelda S M, DeLisser H M
Abstract excerpt
PECAM-1/CD31 is vascular cell adhesion and signaling molecule of the Ig superfamily that plays a role in neutrophil recruitment at inflammatory sites and may be involved the release of leukocytes from the bone marrow and in cardiovascular development. The interactions of PECAM-1 with its ligands...
Topics
- Animals
- Antigens, Differentiation, Myelomonocytic
- Cell Adhesion
- Cell Adhesion Molecules
- Cell Aggregation
- Cytoplasm
- Exons
- Humans
- Immunoglobulins
- L Cells
- Mice
- Molecular Structure
- Mutation
- Platelet Endothelial Cell Adhesion Molecule-1