Article
Rapid activation of Rac GTPase in living cells by force is independent of Src.
PloS one - 18 Nov 2009
Poh Yeh-Chuin, Na Sungsoo, Chowdhury Farhan, Ouyang Mingxing, Wang Yingxiao, Wang Ning
Abstract excerpt
It is well known that mechanical forces are crucial in regulating functions of every tissue and organ in a human body. However, it remains unclear how mechanical forces are transduced into biochemical activities and biological responses at the cellular and molecular level. Using the magnetic twisting cytometry technique, we applied local mechanical stresses to living human airway smooth muscle cells with a...
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