Article
Voxel-based morphometric brain comparison between healthy subjects and major depressive disorder patients in Japanese with the s/s genotype of 5-HTTLPR.
Scientific reports - 21 Jun 2017
Igata Natsuki, Kakeda Shingo, Watanabe Keita, Ide Satoru, Kishi Taro, Abe Osamu, Igata Ryouhei, Katsuki Asuka, Iwata Nakao, Yoshimura Reiji, Korogi Yukunori
Abstract excerpt
Individuals with s/s genotype of serotonin transporter gene-linked promotor region (5-HTTLPR), which appear with a high frequency in Japanese, exhibit more diagnosable depression in relation to stressful life events than those with the s/l or l/l genotype. We prospectively investigated the brain volume changes in first-episode and medication naïve major depression disorder patients (MDD) with the s/s genotype in...
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