Article
Characterization of human FCRL4-positive B cells.
PloS one - 1 Jan 2017
Jourdan Michel, Robert Nicolas, Cren Maïlys, Thibaut Coraline, Duperray Christophe, Kassambara Alboukadel, Cogné Michel, Tarte Karin, Klein Bernard, Moreaux Jérôme
Abstract excerpt
FCRL4 is an immunoregulatory receptor that belongs to the Fc receptor-like (FCRL) family. In healthy individuals, FCRL4 is specifically expressed by memory B cells (MBCs) localized in sub-epithelial regions of lymphoid tissues. Expansion of FCRL4+ B cells has been observed in blood and other tissues in various infectious and autoimmune disorders. Currently, the mechanisms involved in pathological FCRL4+ B cell...
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