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Article

Antibodies Encoded by FCRL4-Bearing Memory B Cells Preferentially Recognize Commensal Microbial Antigens.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2018

Liu Yanling, McDaniel Jonathan R, Khan Srijit, Campisi Paolo, Propst Evan J, Holler Theresa, Grunebaum Eyal, Georgiou George, Ippolito Gregory C, Ehrhardt Götz R A

Abstract excerpt

FCRL4, a low-affinity IgA Ab receptor with strong immunoregulatory potential, is an identifying feature of a tissue-based population of memory B cells (Bmem). We used two independent approaches to perform a comparative analysis of the Ag receptor repertoires of FCRL4+ and FCRL4- Bmem in human tonsils. We determined that FCRL4+ Bmem displayed lower levels of somatic mutations in their Ag receptors compared with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29703863
DOI: 10.4049/jimmunol.1701549
PMCID: PMC5988966

Genes

FCRL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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