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Article

Multiplexed live-cell imaging for drug responses in patient-derived organoid models of cancer

2023-11-17

Abstract excerpt

<h4>ABSTRACT</h4> Patient-derived organoid (PDO) models of cancer are a multifunctional research system that better recapitulates human disease as compared to cancer cell lines. PDO models can be generated by culturing patient tumor cells in extracellular basement membrane extracts (BME) and plating as three-dimensional domes. However, commercially available reagents that have been optimized for phenotypic assays...

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Literature Corpus work
603b42cf-546b-58ba-8345-8c638ed03367
DOI
10.1101/2023.11.15.567243
Open publication

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Multiplexed live-cell imaging for drug responses in patient-derived organoid models of cancerDOI 10.1101/2023.11.15.567243
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