Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

rqt: an R package for gene-level meta-analysis.

Bioinformatics (Oxford, England) - 1 Oct 2017

Zhbannikov Ilya Y, Arbeev Konstantin G, Yashin Anatoliy I

Abstract excerpt

MOTIVATION: Despite recent advances of modern GWAS methods, it is still remains an important problem of addressing calculation an effect size and corresponding p-value for the whole gene rather than for single variant. RESULTS: We developed an R package rqt, which offers gene-level GWAS meta-analysis. The package can be easily included into bioinformatics pipeline or used stand-alone. We applied this tool to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Genes
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Meta-Analysis as Topic

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 28633423
DOI: 10.1093/bioinformatics/btx395
PMCID: PMC5860520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

rqt: an R package for gene-level meta-analysis.PMID 28633423Read ↗

Genome-Wide Association Analysis Using R.Semantic proximity Read ↗

Metasubtract: an R-package to analytically produce leave-one-out meta-analysis GWAS summary statistics.Semantic proximity Read ↗

From SNP to pathway-based GWAS meta-analysis: do current meta-analysis approaches resolve power and replication in genetic association studies?Semantic proximity Read ↗

Meta-analysis methods for genome-wide association studies and beyond.Semantic proximity Read ↗

METAINTER: meta-analysis of multiple regression models in genome-wide association studies.Semantic proximity Read ↗

Addressing Overlapping Sample Challenges in Genome-Wide Association Studies: Meta-Reductive ApproachSemantic proximity Read ↗

Reproduction and In-Depth Evaluation of Genome-Wide Association Studies and Genome-Wide Meta-analyses Using Summary Statistics.Semantic proximity Read ↗

Methods for meta-analysis of genetic data.Semantic proximity Read ↗

The Geometric Increase in Meta-Analyses from China in the Genomic EraSemantic proximity Read ↗

A novel statistical framework for meta-analysis of total mediation effect with high dimensional omics mediators in large-scale genomic consortiaSemantic proximity Read ↗

Meta-analysis for model-free methods.Semantic proximity Read ↗

LDSC regression-based heritability estimates can be biased when summary statistics are obtained from meta-analysis or imputed variantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.