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Article

Reproduction and In-Depth Evaluation of Genome-Wide Association Studies and Genome-Wide Meta-analyses Using Summary Statistics.

G3 (Bethesda, Md.) - 10 Mar 2017

Niu Yao-Fang, Ye Chengyin, He Ji, Han Fang, Guo Long-Biao, Zheng Hou-Feng, Chen Guo-Bo

Abstract excerpt

In line with open-source genetics, we report a novel linear regression technique for genome-wide association studies (GWAS), called Open GWAS algoriTHm (OATH). When individual-level data are not available, OATH can not only completely reproduce reported results from an experimental model, but also recover underreported results from other alternative models with a different combination of nuisance parameters using...

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Identifiers

PMID: 28122950
DOI: 10.1534/g3.116.038877
PMCID: PMC5345724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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