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Article

Genome-wide epigenetic data facilitate understanding of disease susceptibility association studies.

The Journal of biological chemistry - 7 Sept 2012

Hardison Ross C

Abstract excerpt

Complex traits such as susceptibility to diseases are determined in part by variants at multiple genetic loci. Genome-wide association studies can identify these loci, but most phenotype-associated variants lie distal to protein-coding regions and are likely involved in regulating gene expression. Understanding how these genetic variants affect complex traits depends on the ability to predict and test the...

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Share to Epigenesis, Genetic
Share to Genetic Loci
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22952232
DOI: 10.1074/jbc.R112.352427
PMCID: PMC3438926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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