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Article

A positive association between the human tissue kallikerin gene A2233C polymorphism and blood pressure response to benazepril.

Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2017

Hong Zhe, Pan Liying, Fei Jiali, Ma Zhangqing, Hong Zongyuan

Abstract excerpt

BACKGROUND: It is generally believed that essential hypertension is influenced by both genetic and environmental factors, as well as their interactions. Tissue kallikrein encoded by the tissue kallikrein gene (KLK1) is a key serine proteinase of kallikrein-kinin system, which is capable of generating potent vasactive peptides, kinins, by selective cleavage of the kininogen substrate. It was reported that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28621557
DOI: 10.1080/10641963.2016.1246557

Genes

KLK1
DBP
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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