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Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases.

Biological chemistry - 1 Dec 2012

Batra Jyotsna, O'Mara Tracy, Patnala Radhika, Lose Felicity, Clements Judith A

Abstract excerpt

The Kallikrein ( KLK ) gene locus encodes a family of serine proteases and is the largest contiguous cluster of protease-encoding genes attributed an evolutionary age of 330 million years. The KLK locus has been implicated asa high susceptibility risk loci in numerous cancer studies through the last decade. The KLK3 gene already has established clinical relevance as a biomarker in prostate cancer prognosis...

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Source

Identifiers

PMID: 23667899
DOI: 10.1515/hsz-2012-0211

Genes

KLK3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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