Article
Microtubule actin crosslinking factor 1 promotes osteoblast differentiation by promoting β-catenin/TCF1/Runx2 signaling axis.
Journal of cellular physiology - 1 Feb 2018
Hu Lifang, Su Peihong, Yin Chong, Zhang Yan, Li Runzhi, Yan Kun, Chen Zhihao, Li Dijie, Zhang Ge, Wang Liping, Miao Zhiping, Qian Airong, Xian Cory J
Abstract excerpt
Osteoblast differentiation is a multistep process delicately regulated by many factors, including cytoskeletal dynamics and signaling pathways. Microtubule actin crosslinking factor 1 (MACF1), a key cytoskeletal linker, has been shown to play key roles in signal transduction and in diverse cellular processes; however, its role in regulating osteoblast differentiation is still needed to be elucidated. To further...
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