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CBFA1: A molecular switch in osteoblast biology

1 Jan 2000

Abstract excerpt

During the past 4 years, our molecular understanding of osteoblast biology has made rapid progress due to the characterization of the function of one molecule, Cbfa1. This member of the runt/Cbfa family of transcription factors was first identified as the nuclear protein binding to an osteoblast-specific cis-acting element activating the expression of Osteocalcin, the most osteoblast-specific gene. Cbfa1 was then...

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PMID: 11084646
DOI: 10.1002/1097-0177(2000)9999:9999<::aid-dvdy1074>3.0.co;2-c

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