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Role and mechanism of Integrin α5β1 in bone formation and disease

14 Aug 2025

Abstract excerpt

Integrin α5β1 is a key signaling protein between cells and the extracellular matrix. It plays crucial roles in biological processes such as cell adhesion, migration, and differentiation. Recent studies have shown that integrin α5β1 is significantly involved in bone formation and related diseases. Integrin α5β1 participates in the differentiation of mesenchymal stem cells into osteoblasts. It interacts with the...

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PMID: 40894924
DOI: 10.3389/fcell.2025.1632710

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