Article
Association of Triglyceride-Related Genetic Variants With Mitral Annular Calcification.
Journal of the American College of Cardiology - 20 Jun 2017
Afshar Mehdi, Luk Kevin, Do Ron, Dufresne Line, Owens David S, Harris Tamara B, Peloso Gina M, Kerr Kathleen F, Wong Quenna, Smith Albert V, Budoff Mathew J, Rotter Jerome I, Cupples L Adrienne, Rich Stephen S, Engert James C, Gudnason Vilmundur, O'Donnell Christopher J, Post Wendy S, Thanassoulis George
Abstract excerpt
BACKGROUND: Mitral annular calcium (MAC), commonly identified by cardiac imaging, is associated with cardiovascular events and predisposes to the development of clinically important mitral valve regurgitation and mitral valve stenosis. However, its biological determinants remain largely unknown. OBJECTIVES: The authors sought to evaluate whether a genetic predisposition to elevations in plasma lipids is...
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