Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein misfolding cyclic amplification corroborates the absence of PrPSc accumulation in placenta from foetuses with the ARR/ARQ genotype in natural scrapie.

Veterinary microbiology - 1 May 2017

Garza María Carmen, Eraña Hasier, Castilla Joaquín, Acín Cristina, Vargas Antonia, Badiola Juan José, Monleón Eva

Abstract excerpt

Ovine scrapie is a worldwide spread prion disease that is transmitted horizontally under field conditions. Placenta from scrapie-infected ewes is an important source of infection, since this tissue can accumulate high amounts of PrPSc depending on the foetal genotype. Therefore, placentas carrying susceptible foetuses can accumulate PrPSc but there is not PrPSc accumulation in presence of foetuses with at least...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fetus
Share to Infectious Disease Transmission, Vertical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Placenta

Share to Prions

Share to Protein Folding

Share to PrPSc Proteins

Share to Scrapie

Source

Identifiers

PMID: 28619160
DOI: 10.1016/j.vetmic.2017.03.034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein misfolding cyclic amplification corroborates the absence of PrPSc accumulation in placenta from foetuses with the ARR/ARQ genotype in natural scrapie.PMID 28619160Read ↗

Detection of PrPres in genetically susceptible fetuses from sheep with natural scrapie.Semantic proximity Read ↗

PrP(Sc) accumulation in placentas of ewes exposed to natural scrapie: influence of foetal PrP genotype and effect on ewe-to-lamb transmission.Semantic proximity Read ↗

In vitro amplification of ovine prions from scrapie-infected sheep from Great Britain reveals distinct patterns of propagation.Semantic proximity Read ↗

Dynamics and genetics of PrPSc placental accumulation in sheep.Semantic proximity Read ↗

Assessment of the genetic susceptibility of sheep to scrapie by protein misfolding cyclic amplification and comparison with experimental scrapie transmission studies.Semantic proximity Read ↗

PrP(Sc) detection and infectivity in semen from scrapie-infected sheep.Semantic proximity Read ↗

In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapieSemantic proximity Read ↗

Differentiating ovine BSE from CH1641 scrapie by serial protein misfolding cyclic amplification.Semantic proximity Read ↗

Pathogenesis, detection, and control of scrapie in sheep.Semantic proximity Read ↗

Naturally occurring scrapie in Southdown sheep.Semantic proximity Read ↗

Rapid testing leads to the underestimation of the scrapie prevalence in an affected sheep and goat flock.Semantic proximity Read ↗

Classic scrapie in sheep with the ARR/ARR prion genotype in Germany and France.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.